PG NEET Biochemistry Mcqs 4 – General Biochemistry

  1. The operating time of the following receptor is in milliseconds
    1. G- Protein-Coupled Receptor
    2. Kinase-linked receptor
    3. Ligand-gated ion channels
    4. Nuclear receptor
      1. Ans(3)
  2. Acute phase reactants are all except
    1. Fibrinogen
    2. Hepcidin
    3. Plasminogen
    4. Serum Amyloid A Protein
      1. Ans(2)
  3. All are increased in acute phase response except
    1. Albumin
    2. Fibrinogen
    3. ESR
    4. CRP
      1. Ans(1)
  4. All are acute phase reactant except
    1. Haptoglobin
    2. Bence Jones protein
    3. CRP
    4. Fibrinogen
      1. Ans(3)
  5. Metabolic activation of procarcinogen is done by the following species of enzymes
    1. Oxidoreductases
    2. Ligases
    3. Cytochrome P450
    4. Xanthine oxidase
      1. Ans(3)
  6. The trace element deficiency which is associated with cardiomyopathy
    1. Selenium
    2. Molybdenum
    3. Manganese
    4. Zinc
      1. Ans(1)
  7. Which one of the following statements concerning vitamin B12 is correct?
    1. The cofactor from is vitamin B12 itself
    2. It is involved in the transfer of amino groups
    3. It requires a specific glycoprotein for its absorption
    4. It is present in plant products
      1. Ans(3)
  8. The most potent form of Vitamin- D is
    1. 1,24,25- tri-hydroxyl cholecalciferol
    2. 24,25- die-hydroxyl  cholecalciferol
    3. 1,25-di-hydroxyl  cholecalciferol
    4. 25- hydroxycholecalciferol
      1. Ans(3)
  9. Prominent organelle of the cell
    1. Nucleus
    2. Mitochondria
    3. Endoplasmic reticulum
    4. Golgi apparatus
      1. Ans(1)
  10.  Microsomal enzyme Marker
    1. ATPase
    2.  Glucose-6 phosphatase
    3. Cathepsin
    4. LDH
      1. Ans(2)
  11. Burning feet syndrome occurs in a deficiency of
    1. Pantothenate
    2. Biotin
    3. Folic acid
    4. Tocopherol
      1. Ans(1)
  12. Majority of lipids in the biological lipid bilayer
    1. Cholesterol
    2. Palmitic acid
    3. Phosphoglycerides
    4. Linoleic acid
      1. Ans(3)
  13. A feature of competitive inhibition
    1. Increased Vmax
    2. Deceased Vmax
    3. Increased Km
    4. Deceased Km
      1. Ans(3)
  14. All are  types of regulation of enzyme activity except:
    1. Allosteric activation
    2. Suicidal inhibition
    3. Competitive inhibition
    4. Covalent inhibition
      1. Ans(3)
  15. Vitamin not synthesized in the human body
    1. Niacin
    2. Vitamin-D
    3. Vitamin-K2
    4. Vitamin-C
      1. Ans(4)
  16. Tetrahydrobiopterin (BH4) is a cofactor for A/E
    1. Tyrosine hydroxylase
    2. 21 -a hydroxylase
    3. Phenylalanine hydroxylase
    4. Tryptophan hydroxylase
      1.  Ans(2)
  17. vegetarians derive vitamin B-12 from
    1. Curd
    2. Green leaves
    3. Fruits
    4. Pulses
      1. Ans(1)
  18. One of the followings is not linked to the generation of free radicals
    1. Ascorbic acid
    2. Xanthine oxidase
    3. NADPH oxidase
    4. N20
      1. Ans(1)
  19. Cytochrome- P450 is present in A/E
    1. Placenta
    2. Liver
    3. Testes
    4. Adrenal cortex
      1. Ans(None of the Above)
  20. Selenium is a Co-factor for
    1. Glutathione reductase
    2. Glutathione peroxidase
    3. Glutathione synthetase
    4. Glutathione dehydrogenase
      1. Ans(2)
  21. Vitamin involved in Carboxylation is
    1. Pantothenic Acid
    2. Biotin
    3. Ascorbic Acid
    4. Niacin
      1. Ans(2)
  22. The parietal factor is essential for
    1. Thiamine
    2. Riboflavin
    3. Cyanocobalamine
    4. Pyridoxine
      1. Ans(3)
  23. An example of Serine protease is
    1. renin
    2. Pepsin
    3. Chymotrypsin
    4. Angiotensin
      1. Ans(3)
  24. Synthesis of Acetyl CoA requires:
    1. Thiamine
    2. Pantothenic Acid
    3. Pyridoxine
    4. Biotin
      1. Ans(2)
  25. Thiamine deficiency is estimated by
    1. RBC transketolase
    2. Pyruvate kinase
    3. Glutathione Peroxidase
    4. Pyruvate dehydrogenase
      1. Ans(1)
  26. All are anti-oxidants excepts
    1. b – Carotene
    2. Vitamin- E
    3. vitamin – D
    4. Ascorbic Acid
      1. Ans(3)
  27. The weakest bond among the following is
    1. Disulphide bond
    2. Hydrogen bond
    3. Covalent bond
    4. Vander Wal forces
      1. Ans(4)
  28. vitamin – K plays a major role in hemostasis by involving in
    1. Heme synthesis
    2. Carboxylation
    3. Decarboxylation
    4. Transamination
      1. Ans(2)
  29. Anti- rachitic Vit is activated in
    1. liver
    2. Lungs
    3. Kidneys
    4. Small intestine
      1. Ans(3)
  30. Glutathione peroxidase contains
    1. Zinc
    2. Copper
    3. Selenium
    4. Iron
      1. Ans(3)
  31. Alkaline phosphatase contains
    1. Cobalt
    2. Zinc
    3. Iron
    4. Copper
      1. Ans(2)
  32. Prothrombin is synthesized in
    1. Liver
    2. Bone marrow
    3. kidney
    4. Endothelium of injured vessel
      1. Ans(1)
  33. Biotin mediated carboxylation involves A/E
    1. pyruvate
    2. Glutamate
    3. Propionyl-CoA
    4. Acetyl  CoA
      1. Ans(2)
  34. Calcitriol is
    1. 25 – hydroxy Cholecalciferol
    2. 1,25 – dihydroxy Cholecalciferol
    3. 24, 25 dihydroxy Cholecalciferol
    4. 1 – hydroxy Cholecalciferol
      1. Ans(2)
  35. Features of thiamine deficiency
    1. Altered RBC transketolase activity
    2. High output Cardiac failure
    3. Wernicke – Korsakoff syndrome
    4. All of the above
      1. Ans(4)
  36. Enzyme that catalyzes the formation of superoxide ion
    1. Superoxide dismutase
    2. Catalase
    3. NADPH oxidase
    4. Myeloperoxidase
      1. Ans(3)
  37. Treatment of Wernick’s encephalopathy
    1. Niacin
    2. Pyridoxine
    3. Riboflavin
    4. Thiamine
      1. Ans(4)
  38. The vitamin deficiency which is not associated with any neurological manifestation is
    1. Vitamin – B1
    2. Vitamin – B12
    3. Vitamin – B6
    4. Vitamin – B2
      1. Ans(4)
  39. Pellagra presents with
    1. Dementia
    2. Diarrhea
    3. Dermatitis
    4. All of the above
      1. Ans(4)
  40. Hypervitaminosis of vitamin A causes:
    1. Teratogenicity
    2. Hyperostosis
    3. Liver damage
    4. All of the above
      1. Ans(4)
  41. Vitamin – A deficiency Causes
    1. Scurvy
    2. Beriberi
    3. Night Blindness
    4. Rickets
      1. Ans(3)
  42. Thiamine acts a Co-enzyme for
    1. Transketolase
    2. Transaldolase
    3. Glucokinase
    4. Pyruvate kinase
      1. Ans(1)
  43. The Cytochrome which plays a major role in drug metabolism
    1. Cytochrome P 136
    2. Cytochrome C 143
    3. Cytochrome D 120
    4. Cytochrome P 450
      1. Ans(4)
  44. The isoenzyme specific for Myocardial Infarction is:
    1. LDH – 4
    2. LDH – 5
    3. LDH – 2
    4. LDH – 1
      1. Ans(4)
  45. Albumin binds with all except:
    1. Steroid hormones
    2. Calcium
    3. Free Fatty acids
    4. Thyroxine
      1. Ans(1,2,3,4)
  46. Anti-oxidant vitamin is
    1. Calciferol
    2. thiamine
    3. Tocopherol
    4. Cyanocobalamine
      1. Ans(3)
  47. Incorporation of carbon units except for methane during oxidation involves
    1. Thiamine
    2. Niacin
    3. Tetra Hydro Folic Acid
    4. Methionine
      1. Ans(3)
  48. Pellagra occurs in a deficiency of
    1. Vitamin-A
    2. Thiamine
    3. Riboflavin
    4. Niacin
      1. Ans(4)
  49. Oxidation can be described as A/ E
    1. Loss of electrons
    2. Addition of oxygen
    3. Removal of hydrogen
    4. Addition of hydrogen
      1. Ans(4)
  50. True regarding competitive enzymatic inhibition are A/E
    1. Reversible Reaction
    2. Inhibited by metal ions
    3. Inhibitor and substrate have a similar structure
    4. Km is altered
      1. Ans(2)

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