NEET PG Medicine MCQs 197 – Endocrinology – 9

1. Features of tumor lysis syndrome are

  1. Hypocalcemia
  2. Hypophosphatemia
  3. Alkalosis
  4. Hypokalemia

Ans (1)


2. True about tumor lysis syndrome are A/E

  1. Hyperuricemia
  2. Hypercalcemia
  3. Hyperkalemia
  4. Hyperphosphatemia

Ans (2)


3. Which of the following is a bony lesion in Vitamin A intoxication?

  1. Bone demineralization
  2. Bone pain
  3. Hyperostosis
  4. All of the above

Ans (4)


4. Hypophosphatemia is seen in all except

  1. Acute renal failure
  2. Resolving phases of diabetic ketoacidosis
  3. Respiratory alkalosis
  4. Chronic alcoholism

Ans (1)


5. Which of the following condition hypophosphatemia can occur?

  1. Hemochromatosis
  2. Wilson’s disease
  3. Budd Chiari syndrome
  4. Hepatoma

Ans (2)


6. Hypocalcemia with hyperphosphatemia are seen in

  1. CRF
  2. Pseudohypoparathyroidism
  3. Vit D deficiency
  4. Magnesium deficiency

Ans (1)


7. A 20 year old male presented with chronic constipation, headache and palpitations. On examination he had marfanoid habitus, neuromas of tongue, medullated corneal nerve fibers and nodule of 2×2 cm size in the left lobe of thyroid gland. This patient is a case of

  1. Sporadic medullary carcinoma of thyroid
  2. Familial medullary carcinoma of thyroid
  3. MEN IIA
  4. MINIIB

Ans (4)

 


8. Type I MEN involves all, EXCEPT:

  1. Pancreas
  2. Adrenal
  3. Pituitary
  4. Parathyroid

Ans (2)


9. All are associated with MEN 2 except

  1. Pheochromocytoma
  2. Islet cell hyperplasia
  3. Medullary carcinoma thyroid
  4. Parathyroid adenoma

Ans (2)

 


10. Pheochromocytoma may be associated with

  1. Medullary carcinoma of the thyroid
  2. Papillary carcinoma of the thyroid
  3. Anaplastic carcinoma of the thyroid
  4. Follicular carcinoma of the thyroid

Ans (1)


11. A 25 yr woman has recurrent episodes of headache and sweating. Her mother had renal calculi and died after having a neck mass. The physical examination reveals a thyroid nodule but no clinical sign of thyrotoxicosis. Before performing thyroid surgery, the surgeon should order:

  1. Measurement of thyroid hormones
  2. Serial determinations of serum calcium, phosphorus protein and alkaline phosphatise
  3. 24 hours urine test for 5 hydroxyindoleacetic acid excretion
  4. Serial 24 hours test for catecholamines, metanephrine and vanillylmandelic acid excretion

Ans (4)

 


12. The most common cause of Cushing’s syndrome is

  1. Pituitary adenoma
  2. Adrenal adenoma
  3. Ectopic ACTH
  4. Latrogenic steroids

Ans (4)


13. All of the following are clinical features of Cushing’s syndrome except

  1. Insulin resistance
  2. Menorrhagia
  3. Violaceous striae
  4. Centripetal obesity

Ans (2)


14. Features not seen in Cushin’s Syndrome is

  1. Hypoglycaemia
  2. Hypertension
  3. Frank psychosis
  4. Hypokalemia

Ans (1)


15. The differentiating feature b/w Ectopic ACTH secretion and Crushing syndrome is

  1. Hypokalemic alkalosis
  2. Clinical features of Cushing syndrome
  3. Hyperpigmentation
  4. Hypertension

Ans (1)


16. Which of the following is the earliest manifestation of Cushing’s syndrome?

  1. Loss of diurnal variation
  2. Increased ACTH
  3. Increased plasma Cortisol
  4. Increase urinary metabolites of Cortisol

Ans (1)


17. Nelson’s syndrome is most likely seen after

  1. Hepophysectomy
  2. Adrenalectomy
  3. Thyroidectomy
  4. Orchidectomy

Ans (2)


18. Which drug is used for medical adrenalectomy?

  1. Metyrapone
  2. Ketoconazole
  3. Trilostane
  4. All of the above

Ans (4)


19. True about Nelson syndrome?

  1. Very high serum ACTH
  2. Pituitary surgery is done
  3. Very aggressive pituitary gland
  4. All are true

Ans (4)


20. Feature of Addison’s disease include all of the following except

  1. Asthenia
  2. Hyperpigmentation
  3. Hypertension
  4. Abdominal pain

Ans (3)


21. Addison’s disease is associated with all except

  1. Cardiac atrophy
  2. Decreased diastolic B.P
  3. Serum cortisol <3 mcg/dl
  4. Low rennin levels

Ans (4)

 


22. Addison’s disease is characterized by following except

  1. Hyperkalemia
  2. Hypotension
  3. Hyponatremia
  4. Hypocalcemia

Ans (4)


23. In Addison’s disease, most diagnostic test is

  1. Serum Na+,K+,rennin
  2. Serum Na+,K+,saline suppression
  3. Serum creatinine/urea ratio
  4. ACTH stimulation test

Ans (4)

 


24. All of the following may be associated with primary aldosteronism, except

  1. Adrenal adenoma
  2. Adrenal hyperplasia
  3. Von-Hippel-Lindau syndrome
  4. Adrenal carcinoma

Ans (3)


25. Increased aldosterone leads to all except

  1. Hypernatremia
  2. Hypokalemia
  3. Hypertension
  4. Metabolic acidosis

Ans (4)

 


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