NEET PG Pathology MCQs 172 – Liver, Gall bladder, Pancreas Disorders – 5

1. In Chronic Hepatitis B (HBV) infection presence of HBeAg (Hepatitis B e antigen) suggests which of the following?

  1. Ongoing viral replication
  2. Resolving infection
  3. Development of cirrhosis
  4. Development of Hepatoma

Ans (1)

2. Most common route hepatitis E transmission is?

  1. Sexual
  2. Faceo-oral
  3. Horizontal
  4. Vertical

Ans (2)

3. Is Gene responsible for the mutation of HBV is?

  1. X geneS
  2. gene
  3. P gene
  4. C gene

Ans (1)

4. A nurse got a needle prick injury. Which of the following suggests an active phase of hepatitis?

  1. IgM Ab of HBc
  2. IgG Ab of HBc
  3. IgG of HBs
  4. Anti HbeAb

Ans (1)

5. The most common subtype of Hepatitis B in North India is?

    1. adr
    2. adw
    3. ayw
    4. ayr

Ans (3)

6. acute hepatitis B can be diagnosed by

    1. HBsAg
    2. IgM anti0HBcAb
    3. HBeAg
    4. IgG anti-HBcAb
    5. Core antigen

Ans (1,2)

7. Hepatitis virus that causes chronic liver disease is?

    1. Hepatitis A
    2. Hepatitis B
    3. Hepatitis C
    4. Hepatitis D

Ans (3)

8. Not a complication of acute viral Hepatitis?

    1. Aplastic anemia
    2. Acute pancreatitis
    3. Autoimmune hepatitis
    4. Hepatocellular carcinoma

Ans (4)

9. A 25-year person presents with mild icterus. His HBsAg +ve, HBeAg -ve with SGOT and SGPT raised 5-6 times the original value. HBV DNA levels were >1,00,000/ml. what is your diagnosis?

    1. Wild type HBV
    2. Surface mutant HBV
    3. Precure mutant HBV
    4. Active HBV carrier

Ans (3)

10.Which of the following is true regarding viral hepatitis

    1. Raised transaminase level correlates well with hepatic injury
    2. Variable elevation of transaminase in the prodromal phase
    3. HAV infection is diagnosed by IgG estimation
    4. Elevation of alkaline phosphatase specific for liver injury

Ans (2)

11. Hallmark of chronic hepatitis

    1. Interface hepatitis
    2. Ballooning degeneration of hepatocytes
    3. Cholestasis
    4. Periportal fibrosis and bridging fibrosis

Ans (4)

12. Ground glass hepatocyte is seen in which hepatitis?

    1. Hepatitis A
    2. Hepatitis B
    3. Hepatitis D
    4. Hepatitis E

Ans (2)

13. Councilman bodies are seen in

    1. Alcoholic cirrhosis
    2. Wilson’s disease
    3. Acute viral hepatitis
    4. Autoimmune hepatitis

Ans (3)

14. Microvesicular fatty change in hepatocytes is seen due to infection with

    1. Hepatitis A
    2. Hepatitis B
    3. Hepatitis C
    4. Hepatitis D

Ans (4)

15. Histopathology of chronic hepatitis shows

    1. Ballooning of hepatocytes
    2. Councilman bodies
    3. Bridging fibrosis
    4. All of the above

Ans (3)

16. Chronic persistent hepatitis and chronic active hepatitis are differentiated by

    1. Anti-Smith Ab
    2. C-Reactive Protein
    3. Arthritis
    4. Liver biopsy

Ans (4)

17. Which of the following is the single most important indicator of the likelihood of progression of hepatitis to liver cirrhosis

    1. Etiology
    2. Associated serological findings
    3. Presence of bridging necrosis
    4. Presence of Mallory hyaline bodies

Ans (1)

18. Micronodular cirrhosis is seen in all except

    1. Chronic hepatitis B
    2. Alcoholic cirrhosis
    3. Hemochromatosis
    4. Chronic cirrhosis secondary to biliary stasis

Ans (1)

19. Histological features of chronic hepatitis include

    1. Fibrosis of portahepatis
    2. Architectural changes
    3. Bridging necrosis
    4. Ballooning degeneration
    5. Mononuclear portal infiltration

Ans (1,3,5)

20. Acute viral hepatitis shows

    1. Ballooning degeneration
    2. Acidophilic inclusion
    3. Interface hepatitis
    4. Lobular disarray
    5. Fibrosis

Ans (1,2,4)

21. The liver biopsy n acute hepatitis due to hepatitis B virus is likely to show all of the following, except

    1. Ballooning change of hepatocytes
    2. Ground glass hepatocytes
    3. Focal or spotty necrosis
    4. Acidophil bodies

Ans (2)

22. In Chronic Viral Hepatitis

    1. Hepatitis A virus infection is a common cause of chronic hepatitis in children
    2. Morphological classification into Chronic Active Hepatitis and Chronic Persistent Hepatitis are important
    3. Fatty change is pathognomonic of Hepatitis C virus infection
    4. Grading refers to the extent of necrosis and inflammation

Ans (4)

23. Acute viral hepatitis is characterized by

    1. Piecemeal necrosis
    2. Zonal necrosis
    3. The liver is enlarged and bile stained
    4. Bridging necrosis
    5. Spotty necrosis

Ans (2,3,4,5)

24. Chronic Active Hepatitis is most reliably distinguished from chronic Persistent hepatitis by the presence of

    1. Extrahepatic manifestations
    2. The significant titer of anti-smooth muscle antibody
    3. Characteristic liver histology
    4. Hepatitis B surface antigen

Ans (3)

25. Pathological change of liver cells in acute viral hepatitis are all except?

    1. Ballooning degeneration
    2. Ground glass hepatocytes
    3. Piecemeal necrosis
    4. Fatty change

Ans (2)

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Most of the questions are from previous papers of  leading universities in India

Repeat questions show the importance of those questions

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