NEET PG Pathology MCQs 175 – Liver, Gall bladder, Pancreas Disorders – 8

1. Centrizonal necrosis of the liver occurs with:

  1. Carbon tetrachloride toxicity
  2. Congestive cardiac failure
  3. smoking
  4. chronic alcoholism

Ans( 1)

2. gilbert’s syndrome true all except:

  1. causes cirrhosis
  2. autosomal dominant
  3. normal liver function test
  4. increased unconjugated bilirubin

Ans(1 )

3. piece meal necrosis on liver biopsy is a feature of:

  1. alcoholic hepatitis
  2. Indian childhood cirrhosis
  3. chronic active hepatitis
  4. primary alcoholic cirrhosis

Ans( 3)

4. Mallory bodies contain:

  1. vimentin
  2. cytokeratins
  3. desmin
  4. collagen

Ans( 2)

5. gene of Wilson’s disease is:

  1. ATP7 A
  2. ATP 7 B
  3. ADP 7 A
  4. ADP 7 B

Ans( 2)

6. Definite markers for hepatoblastoma is:

  1. LDH
  2. Alpha-fetoprotein
  3. HCG
  4. Alkaline phosphatase

Ans( 2)

7. Most common benign tumor of liver is:

  1. papilloma
  2. hepatic adenoma
  3. ameboma
  4. hemangioma

Ans(4 )

8. all are features of hepatocellular carcinoma except::

  1. not common in Asian
  2. liver biopsy is diagnostic
  3. raised titre if HBV and HCV antibodies
  4. fibrolamellar type is having good prognosis

Ans( 1)

9. Klatskin’s tumor is:

  1. nodular type of cholangiocarcinoma
  2. fibrolamellar HCC
  3. gall bladder carcinoma
  4. HCC

Ans(1)

10. Sclerosing cholangitis is associated with:

  1. Ulcerative colitis
  2. Celiac sprue
  3. Wilson’s disease
  4. Whipple’s disease

Ans(1 )

11. Chronic active hepatitis seen in:

  1. Methyl dopa
  2. oestrogen
  3. erythromycin
  4. tetracycline

Ans(1 )

12. major source of collagen is:

  1. Kupfer cells
  2. ito cell
  3. hepatocyte
  4. canalicular cell

Ans( 2)

13. onion skin fibrosis of bile duct is seen in:

  1. primary biliary cirrhosis
  2. primary sclerosing cholangitis
  3. extrahepatic biliary fibrosis
  4. congenital hepatic fibrosis

Ans( 2)

14. gall stones in haemolytic anemia are

  1. pigment
  2. mixed
  3. cholesterol
  4. any type

Ans(1 )

15. An alcoholic patient has portal hypertension and varices. Which of following histologic changes is most likely to be seen in a biopsy specimen taken from his esophagus?

  1. Metaplastic columnar epithelium
  2. Decreased ganglion cells in the myenteric plexus
  3. Dilated blood vessels in the submucosa
  4. Mucosal outpouchings

Ans(3)

16. All are seen in alcoholic hepatitis except:

  1. Panlobular or panacinar steatosis
  2. Microvesicular steatosis
  3. Piecemeal necrosis
  4. Ballooning degeneration of hepatocytes

Ans(2)

17. Mallory hyaline bodies are present in all except:

  1. Alcoholic cirrhosis
  2. Indian childhood cirrhosis
  3. Primary biliary cirrhosis
  4. Secondary biliary cirrhosis

Ans(4)

18. Which one of the following clinical procedures or tests should be used to confirm a diagnosis of nonalcoholic steatohepatitis?

  1. Abdominal magnetic resonance imaging
  2. Liver biopsy
  3. Liver ultrasonography
  4. Oral cholecystogram

Ans(2)

19. Mallory bodies are composed of:

  1. Fat droplets
  2. Mitochondria
  3. Lysosomal enzymes
  4. Intermediate filaments

Ans(4)

20. Alcoholic hyaline is seen in alcoholic liver disease composed of:

  1. Lipofuscin
  2. Eosinophilic intracytoplasmic inclusions
  3. Basophilic intracytoplasmic inclusions
  4. Hemozoin

Ans(2)

21. In Alcoholic liver disease, which of the following pigments is deposited in the hepatocytes?

  1. Hemosiderin
  2. Hemoglobin
  3. Lipofuscin
  4. Melanin

Ans(1)

22. Focal or confluent periportal necrosis along with ballooning degeneration of hepatocytes with or without Mallory bodies and megamitochondria is suggestive:

  1. Acute Hepatitis B
  2. Chronic Hepatitis B
  3. Alcoholic liver injury
  4. Primary HCC

Ans(3)

23. Which of the following is not a feature of Alcoholic liver disease?

  1. Macrovesicular fat within hepatocytes
  2. Lipogranuloma
  3. Lymphocytic infiltration of portal tracts
  4. Portal & sinusoidal collagen deposits

Ans(3)

24. The sign of reversible injury in the case of alcoholic liver disease:

  1. Loss of cell membrane
  2. Nuclear karyolysis
  3. Cytoplasmic vacuole
  4. Pyknosis

Ans(3)

25. An obese female presented with features of hepatitis. She is a known diabetic. Which of the following would be the liver biopsy feature?

  1. NASH
  2. Hepatocyte necrosis
  3. Cirrhosis
  4. Lipoid necrosis

Ans(1)


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