NEET PG Pathology MCQs 178 – Liver, Gall bladder, Pancreas Disorders – 11

1. Hepatocellular damage of Wilson’s resembles-

  1. Acute hepatitis
  2. Chronic hepatitis
  3. Cholestasis
  4. Macrovesicular steatosis
  5. Mallory bodies

Ans(1,2,3,4,5)

2. Raised iron content is NOT found in which organ in Hemochromatosis-

  1. Heart
  2. Skin
  3. Testis
  4. Pituitary

Ans(3)

3. Micronodular cirrhosis is found in:

  1. Jejunoileal bypass
  2. Wilson’s disease
  3. Hemochromatosis
  4. Chronic hepatitis B infection
  5. Chronic hepatitis C infection

Ans(1,3)

4. True statements about a1 anti-trypsin deficiency

  1. Autosomal dominant disease
  2. Emphysema
  3. Fibrosis of portal tract
  4. Diastase resistant PAS positive hepatocytes
  5. Orcein positive granules

Ans(2,3,4)

5. True about alpha-1 antitrypsin deficiency is/are

  1. Autosomal dominant
  2. Pulmonary emphysema
  3. Diastase resistant globules in hepatic cells
  4. Hepatic, cells are orce stain positive
  5. Associated with berry aneurysm

Ans(2,3)

6. Which of the following features in liver biopsy is seen in alpha 1 antitrypsin deficiency

  1. PAS-positive and distrase resistant globules
  2. Cirrhosis of liver
  3. Mallory hyaline
  4. Bile duct proliferation
  5. Amyloid deposition

Ans(1,2,3)

7. Tests to diagnose Wilson’s disease are

  1. KF ring
  2. Liver copper=300 ug/gm of dry weight
  3. Serum ceruloplasmin
  4. 24 hours of urine copper after penicillamine
  5. Serum copper levels

Ans(1,2,3,4)

8. Which of the following has best prognosis

  1. Fibrolamellar variant of HCC
  2. Hemangiosarcoma
  3. Adenosarcoma
  4. Hepatocellular Ca

Ans(1)

9. True about fibrolamellar carcinoma of liver:

  1. Better prognosis than typical hepatocellular carcinoma
  2. Associated with cirrhosis
  3. AFP-positive
  4. Occur in younger adults
  5. More common in females

Ans(1)

10. All are true about focal nodular hyperplasia except:

  1. Multiple nodule may present
  2. More common in male
  3. May be associated with contraceptive pills use
  4. Hypovascular on the arterial-phase and hypervascular on the delayed phase CT images
  5. CT is less sensitive than MRI in depicting the characteristic central scar

Ans(2)

11. Regarding carcinoma gall bladder following features are true except:

  1. One can have similar presentation with benign biliary disease
  2. Squamous cell carcinoma is 40% of all cases
  3. Most patients present with advanced disease
  4. Prognosis is poor

Ans(2)

12. Which of the following is not true about alcoholic cirrhosis:

  1. On many occasions alcoholic hepatitis and alcoholic cirrhosis coexist
  2. Concomitant HIV infection accelerates it
  3. Starts with macronodular and later on changes to micronodular cirrhosis
  4. 10-40 % remains clinically silent

Ans(3)

13. Which of the following do not cause hepatocellular ca

  1. Hepatitis B
  2. Tyrosinemia
  3. Alcoholism
  4. Non alcoholic fatty liver disease

Ans(2)

14. Angiosarcoma of the liver can occur due to occupational exposure to

  1. Asbestos
  2. benzene
  3. vinyl chloride
  4. toluene

Ans( 3)

15. hepatic adenoma is most common in:

  1. young males
  2. young female
  3. old males
  4. old females

Ans(2)

16. which liver tumor has the best prognosis

  1. hepatocellular carcinoma
  2. hemangiosarcoma
  3. hemangioblastoma
  4. fibrolamellar carcinoma

Ans( 4)

17. not true about HNF1-a inactivated hepatocellular adenomas

  1. mostly in women
  2. high risk of malignant transformation
  3. associated with MODY-3
  4. OCPs are implicated in pathogenesis

Ans(2)

18. Not true about hepatoblastoma

  1. Most common in children
  2. Mature hepatocytes present
  3. Not associated with cirrhosis
  4. Fatal if untreated

Ans(2)

19. Which of the following is NOT a risk factor for hepatocellular carcinoma

  1. A1-antitrypsin deficiency
  2. NASH/NAFLD
  3. Chronic alcoholism
  4. Hepatitis D

Ans(4)

20.Which malignancy is associated with liver cirrhosis

  1. Hepatocellular Ca
  2. Cholangiocarcinoma
  3. Fibrolamellar Ca
  4. Pancreatic Ca

Ans(1)

21. Which is a risk factor for cholangiocarcinoma

  1. Persistent hepatitis
  2. Ulcerative colitis
  3. Crohn’s ds
  4. Chronic cholecystitis

Ans(2)

22. Vinyl chloride is associated with which carcinoma

  1. Liver
  2. Spleen
  3. Lung
  4. Prostrate

Ans(1)

23. True about fibrolamellar variant of HCC

  1. Better prognosis than primary HCC
  2. More common in elderly
  3. Raised AFP seen
  4. Underlying cirrhosis not a risk factor
  5. Neurotensin is a biomarker

Ans(1,4,5)

24. Periportal fibrosis is caused by

  1. Methotrexate
  2. Phenytoin
  3. Thorotrast
  4. Halothane

Ans(1)

25. Thorium dioxide causes

  1. Lymphoma
  2. Lymphangiosarcoma
  3. Angiosarcoma
  4. Hemangioendothelioma

Ans( 3)


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