Dermatology MCQs 1 – Developmental & Pigmentation Disorders and Drug Eruptions Collagen Vascular Diseases

  1. True about acanthosis nigricans
    1. Most commonly seen in obesity
    2. seen in the axilla
    3. It signifies internal malignancy
    4. It is associated with insulin resistance
      1. Ans(1)
  2. Acanthosis Nigrivans in old. Pt. Usually indicated
    1. Skin disorder
    2. Malignancy
    3. Senile brain
    4. Usually found in negro
      1. Ans(2)
  3. Acanthosis nigricans histological show
    1. Papillomatosis
    2. Marked acanthosis
    3. Hypermelanosis
    4. all of the above
      1. Ans(1)
  4. Diffuse form of hyperpigmentation is seen in
    1. Vitamin B12 deficiency
    2. Ectopic ACTH secretion
    3. Whipple’s’ disease
    4. All of the above
      1. Ans(4)
  5. A 20 yr old young female had the history of recurrent acne on the face with many antibiotic like clindamycin tetracycline, erythromycin and others. Now she complained of multiple hyperpigmented spots at the site of old acne lesions. Which of the following drug might have been responsible for this:
    1. Erythromycin
    2. Tetracycline
    3. Minocycline
    4. Demeclocycline
      1. Ans(3)
  6. A 17 yr old girl with acne has been taking a drug for the last two years. She now presents with blue black pigmentation of nails. The likely medication causing the above pigmentation is
    1. Tetracycline
    2. Minocycline
    3. Doxycycline
    4. Azithromycin
      1. Ans(2)
  7. Rain drop pigmentation is seen in
    1. Chronic lead poisoning
    2. Chronic Arsenic poisoning
    3. Chronic Mercury poisoning
    4.  All of the above
      1. Ans(2)
  8. Topical azelaic acid is used in
    1. Hyper pigmentary disorder
    2. Dermatophyte infections
    3. Vitiligo
    4. Mixed infection
      1. Ans(4)
  9. Defective. DNA repair is associated with
    1. Xeroderma pigmentosum
    2. Albinism
    3. Ichthyosis
    4. Vitiligo
      1. Ans(1)
  10. Vesiculobullous lesions are not seen in
    1. Pemphigoid
    2. Pemphigus
    3. Scabies
    4. Dermatitis herpetiformis
      1. Ans(1)
  11. Tzanck test is used in the diagnosis of
    1. Epidermolysis Bullosa
    2. Bullous impetigo
    3. Pemphigus
    4. Tinea corporis
      1. Ans(3)
  12. Target lesions are seen in
    1. Urticaria
    2. Erythema multiforme
    3. Scabies
    4. Lichen planus
      1. Ans(3)
  13. A 32-year-old woman receives amoxicillin/clavulanate for presumed bacterial sinusitis. One week later she presents with a diffuse itchy rash. Her mucus membranes are normal. Which of the following is the most likely diagnosis?
    1. Morbilliform drug eruption
    2. Pemphigus Vulgaris
    3. Stevens – Johnson syndrome
      1. Ans(1)
  14. A drug with a high incidence of cutaneous reactions includes the following except:
    1. Sulfonamides
    2. Ampicillin
    3. Erythromycin
    4. Phenytoin
      1. Ans(3)
  15. Side effects of cyclosporine include the following except
    1. Hypertrichosis
    2. Gum hyperplasia
    3. Reticulate pigmentation
    4. Induction of hypertension
      1. Ans(3)
  16. Recurrent plaques on glans which heal with residual hyper pigmentation
    1. Aphthous ulcer
    2. Fixed drug Eruption
    3. Herpes simplex
    4. Chlamydial inf
      1. Ans(2)
  17. Lupus like the picture is not caused by:
    1. INH
    2. Hydralazine
    3. Chloroquine
    4. Procainamide
      1. Ans(3)
  18. Chloroquine is used in the treatment of:
    1. Discoid lupus erythematosus
    2. Lichen planus
    3. Psoriasis
    4. Pemphigoid
      1. Ans(1)
  19. Gottron’s papules or sign is seen in
    1. Dermatomyositis
    2. Acute myeloid leukemia
    3. Psoriasis
    4. Multiple myeloma
      1. Ans(1)
  20. Lilac colored heliotrope pigmentation over the face characteristic of:
    1. Dermatomyositis
    2. Polymyositis
    3. SLE
    4. Systemic sclerosis
      1. Ans(1)
  21. Amongst the connective tissue disorders, malignancy most frequently associated with
    1. Rheumatoid arthritis
    2. SLE
    3. Scleroderma
    4. Dermatomyositis
      1. Ans(4)
  22. A 22 yr old female has brown macular lesions over the bridge of the nose and on the cheek, following exposure to light. The most probable diagnosis is:
    1. Chloasma
    2. SLE
    3. Photodermatitis
    4. Acne rosacea
      1. Ans(1)
  23. A girl aged 19 years presents with arthritis and a photosensitive rash on the cheek. Diagnosis is:
    1. SLE
    2. Chloasma
    3. Stevens- Johnson syndrome
    4. Lyme disease
      1. Ans(1)
  24. The connective tissue disease in which Raymond’s Phenomenon is most common is:
    1. SLE
    2. Systemic sclerosis
    3. Dermatomyositis
    4. Polymyositis
      1. Ans(2)
  25. ”En coup de sabre’ is a form of
    1. Pemphigus Vulgaris
    2. Psoriasis
    3. Lichen planus
    4. Localized scleroderma
      1. Ans(4)
  26. An autoimmune disease is:
    1. Pemphigus Vulgaris
    2. Psoriasis
    3. Lichen planus
    4. Acne Vulgaris
      1. Ans(1)
  27. All are manifestations of SLE except
    1. Lesions resembling Che. DLE
    2. Butterfly rash
    3. Photosensitivity
    4. Sex ratio in nearly equal
      1. Ans(4)
  28. All of the following are cause of “lupus” except
    1. Hydralazine
    2. Clofibrate
    3. Penicillamine
    4. Chlorpromazine
      1. Ans(2)
  29. True about drug induced SLE is
    1. CNS manifestation are common
    2. Renal involvement is common
    3. Anti-histone antibodies are found in many and Sex ratio in nearly equal
    4. All with antibodies progress to lupus
      1. Ans(3)
  30. A 40 yr old women presented with a month history of erythema and swelling of the periorbital region & papules & plaques an the dorsolateral aspect of forearms & knuckles with ragged cuticles. There was no muscle weakness. The most likely diagnosis is
    1. SLE
    2. Dermatomyositis
    3. Systemic sclerosis
    4. Mixed connective tissue disorder
      1. Ans(2)
  31. Gottron’s papules are
    1. Erythematous papules on cheeks
    2. Erythema seen over elbows and knees
    3. Periorbital lesions
    4. Violaceous papules over knuckles
      1. Ans(4)
  32. Gottron papules seen in dermatomyositis are
    1. Erythematous papules on cheeks
    2. Erythema seen over elbows and knees
    3. Periorbital lesions
    4. Violaceous papules over knuckles
      1. Ans(3)
  33. All are dermatological manifestations of dermatomycosis except
    1. Gottron’s patches
    2. Mechanic’s hands
    3. Periungual telangiectasia
    4. Salmon Rash
      1. Ans(4)
  34. All are seen in dermatomyositis except
    1. Calcinosis cutis
    2. Heliotropic rash
    3. Shawl sign
    4. Gottron’s rash
      1. Ans(1)
  35. All are cutaneous manifestations of systemic sclerosis except
    1. Sclerodactyly
    2. Gottron’s papule
    3. Telangiectasis
    4. Esophageal dysmotility
      1. Ans(2)
  36. Female presents with a history of color change from pallor to cyanosis exposure to cold in fingers. Is this condition mostly associated with?
    1. Scleroderma
    2. Leukemia
    3. Lung infections
    4. Hepatosplenomegaly
      1. Ans(1)
  37. Palpable purpura is seen in all except
    1. Wegener’s GN
    2. ITP
    3. HSP
    4. Serum sickness
      1. Ans(2)
  38. Palpable purpura is seen in all conditions except
    1. Cryoglobulinemia
    2. H.S purpura
    3. Gaint cell arteritis
    4. Drug induced vasculitis
      1. Ans(3)
  39. Palpable purpura is seen in
    1. PAN
    2. ITP
    3. TIPDIC
      1. Ans(1)
  40. “Pinch” purpura is diagnosis of
    1. Systemic primary amyloidosis
    2. Secondary systemic amyloidosis
    3. Idiopathic thrombocytopenic purpura
    4. Durg induced purpura
      1. Ans(1)
  41. Which of the following is /are not  the feature of Henoch Schonlein Purpura
    1. Abdominal pain
    2. Splinter hemorrhage
    3. Thrombocytopenia
    4. Epistaxis
      1. Ans(3)
  42. A child develops non- blanching macules and papules on lower extremities, mild abdominal pain and skin biopsy showed IgA deposition. Most appropriate diagnosis is
    1. Drug induced vasculitis
    2. HSP
    3. Wegener’s granulomatosis
    4. Kawasaki disease
      1. Ans(2)
  43. A 42 yr old female has palpable purpura with rash over buttocks, pain in abdomen and arthropathy diagnosis is:
    1. Swee syndrome
    2. HSP
    3. Purpura fulrninans
    4. Meningococcemia
      1. Ans(2)
  44. IgA deposits on skin biopsy
    1. Henoch Schollein purpura
    2. Giant cell arteritis
    3. Microscopic polyangiitis
    4. Wegener’s granulomatosis
      1. Ans(1)
  45. All regarding HSp is true except
    1. Hematuria resolve without treatment
    2. Steroids best treat skin lesions
    3. Self – limiting arthralgia
    4. Excellent prognosis
      1. Ans(2)
  46. A 27 yr old sexually active male develops a vesiculobullous lesion on the glans soon after taking tablet paracetamol for fever. The lesion healed with hyperpigmentation. The most likely diagnosis is:
    1. Behcet’s syndrome
    2. Herpes genitalis
    3. Fixed drug eruption
    4. Pemphigus Vulgaris
      1. Ans(3)
  47. The sexulayy active male comes with complaints of recurrent ulcers over the glans which heals with hyperpigmentation probable diagnosis is:
    1. Aphthous ulcer
    2. Fixed drug eruption
    3. Herpes genitalis
    4. Chlamydial   infection
      1. Ans(1)
  48. Fixed drug eruptions can be seen more frequently with
    1. penicillin
    2. sulfonamide
    3. Cetriizine
    4. Roxithromycin
      1. Ans(2)
  49. Which of these statements is false for lesions of Erythema nodosum
    1. They are considered as hypersensitivity reaction
    2. The skin overlying the lesions is red smooth and shiny
    3. They are usually nontender
    4. They can be associated with tuberculosis
      1. Ans(3)
  50. Erythema nodosum is due to
    1. Contraceptive pills
    2. Barbiturates
    3. Penicillin
    4. Sulfonamides
      1. Ans(1)

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