NEET PG Pathology MCQs 1 – Cell – 1

  1. Cell to cell permeability occurs through
    1. occludin
    2. Zona adherens
    3. connexins
    4. zonulin
      1. Ans(3)
  2. Oval stem cells are located in
    1. canal of schlemn
    2. canal of herring
    3. space of Disse
    4. basal lamina of myotubules
      1. Ans(2)
  3. The tensile strength of tendon depends of
    1. Fibrillin
    2. collagen
    3. fibronectin
    4. elastin
      1. Ans(2)
  4. Stem cells are presents in?
    1.  cornea
    2. base of crypts
    3. bile duct of the liver
    4. mesonephros
      1. Ans(2)
  5. which of the following mechanism is mainly involved in Genomic imprinting?
    1. methylation
    2. acetylation
    3. deamination
    4. phosphorylation
      1. Ans(1)
  6. Does the human genome contain?
    1. 3.2 billion DNA base pairs
    2. 2.3 billion DNA base pairs
    3. 3.2 million DNA base pairs
    4. 2.3 million DNA base pairs
      1. Ans(1)
  7. The term pathology was coined by?
    1. robert Kochs
    2. rudolf Virchow
    3. Lois Pasteur
    4. Gregor Mendel
      1. Ans(2)
  8. Protein-encoding genes comprise what percentage of the genome
    1. 98.5%
    2. 1.5%
    3. 5%
    4. 95%
      1. Ans(2)
  9. Which collagen is typical of basement membrane?
    1. Type I
    2. Type V
    3. Type IV
    4. Type III
      1. Ans(3)
  10. jumping genes take part in:
    1. Gene regulation
    2. chromosomal aberrations
    3. gene movement in a species
    4. carry out gene amplification
      1. Ans(1)
  11. which of the following function is done by RNA I in a gene?
    1. Knockin
    2. Knock out
    3. knock down
    4. knock up
      1. Ans(3)
  12. The most common form of DNA variation is?
    1. single nucleotide polymorphism
    2. copy Number variation
    3. transposons
    4. mutations
      1. Ans(1)
  13. All of the following are Intermediate filament except?
    1. Lamin
    2. cadherin
    3. vimentin
    4. desmin
      1. Ans(2)
  14. Does linkage disequilibrium refer to?
    1. nerve co-inherited gene
    2. inherited but not with disease-causing gene
    3. genetic mutations
    4. Co-inherited with the disease-causing gene
      1. Ans(4)
  15. Does tight junction consist of all except?
    1. occludin
    2. claudin
    3. zonulin
    4. cadherin
      1. Ans(4)
  16. Heritable changes in gene expression not caused alterations in DNA sequence refers to?
    1. genetics
    2. epigenetics
    3. mutations
    4. transposons
      1. Ans(2)
  17. titin protein mutated in?
    1. DCM
    2. HOCM
    3. RCM
    4. non-functional cardiomyopathy
      1. Ans(1)
  18. Do epigenetic factors refer to?
    1. Histone methylation
    2. histone phosphorylation
    3. DNA methylation
    4. all of the above
      1. Ans(4)
  19. peripheral protein in cell membranes are attached by?
    1. GPL
    2. desmosome
    3. catenins
    4. cadherins
      1. Ans(1)
  20. the function of peroxisomes is?
    1. protein synthesis
    2. carbohydrate metabolism
    3. generating H2O2
    4. DNA  replication
      1. Ans(3)
  21. Biding fibrosis in large wounds is due to:
    1. Keratinocyte growth factor
    2. epidermal growth factor
    3. platelet-derived growth factor
    4. transforming growth factor – β
      1. Ans(4)
  22. Does collagen present in cornea?
    1. type 1
    2. type 2
    3. type 4
    4. type 7
      1. Ans(1)
  23. A major cytokine involved in fibrosis
    1. transforming growth factor -α
    2.  transforming growth factor  – β
    3. fibroblast growth factor
    4. epidermal growth factor
      1. Ans(2)
  24. gene silencing RNA
    1. rRNA
    2. tRNA
    3. miRNA
    4. none
      1. Ans(3)
  25. Type of college playing an important role in wound healing
    1. I and III
    2. II and V
    3. III and IV
    4. V and IX
      1. Ans(1)

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