NEET PG Pathology MCQs 10 – Cell – 10

  1. The Fenton reaction leads to free radical generation when?
    1. radiant energy is absorbed by water
    2. hydrogen peroxide is formed by myeloperoxidase
    3. ferrous ions are converted to ferric ions
    4. nitric oxide is converted to the peroxynitrite anion
      1. Ans(3)
  2. when neutrophils show degenerative changes in which the nucleus has undergone fragmentation. this process is known as:
    1. caseous necrosis
    2. coagulation necrosis
    3. karyolysis
    4. karyorrhexis
      1. Ans(4)
  3. An enzyme that protects the brain from free radical injury is:
    1. myeloperoxidase
    2. superoxide dismutase
    3. MAO
    4. Hydroxylase
      1. Ans(2)
  4. 67 yr-old women with a past history of myocardial infarction have the lesion seen here grossly in the brain. Which of the following is the most likely diagnosis?
    1. organizing abscess
    2. acute meningitis
    3. liquefactive necrosis
    4. metastatic carcinoma
      1. Ans(3)
  5. Cells are seen in chronic infection of Pseudomonas:
    1. neutrophils
    2. Eosinophils
    3. lymphocytes
    4. macrophage
      1. Ans(1)
  6. Necrosis means
    1. efflux  of calcium
    2. swelling of cell
    3. enzymatic degradation
    4. fat deposition
      1. Ans(3)
  7. cells most sensitive to hypoxia are:
    1. myocardial cells
    2. neurons
    3. hepatocytes
    4. renal tubular epithelial cells
      1. Ans(2)
  8. fat necrosis  is common in:
    1. omentum
    2. breast
    3. retroperitoneal fat
    4. all of the above
      1. Ans(2)
  9. All of the following statements are true regarding reversible cell injury except:
    1. formation of amorphous densities in the mitochondrial matrix
    2. diminished generation of adenosine triphosphate
    3. formation of blebs in the plasma membrane
    4. a detachment of ribosomes from the granular endoplasmic reticulum
      1. Ans(1)
  10. Fibrinoid necrosis may be observed in all of the following except:
    1. malignant hypertension
    2. polyarteritis nodosa
    3. diabetic glomerulosclerosis
    4. aschoff’s nodule
      1. Ans(3)
  11. Both hyperplasia and hypertrophy are found in:
    1. pregnancy uterus
    2. cardiac muscle in cardiomegaly
    3. skeletal muscle in an athlete
    4. breast development in puberty
      1. Ans(1)
  12. a characteristic feature of apoptosis?
    1. cell membrane intact
    2. cytoplasmic eosinophilia
    3. nuclear molding
    4. cell swelling
      1. Ans(1)
  13. All of the following statements are true regarding reversible cell injury except;
    1. formation of amorphous densities in the mitochondrial matrix
    2. diminished generation of adenosine triphosphate
    3. formation of blebs in the plasma membrane
    4. the detachment of ribosomes from the granular endoplasmic reticulum
      1. Ans(1)
  14. which of the following organelles plays a pivotal role in apoptosis?
    1. mitochondria
    2. endoplasmic reticulum
    3. nucleus
    4. golgi apparatus
      1. Ans(1)
  15. all are reversible pathological changes except:
    1. hydropic swelling
    2. fatty change
    3. visible vacuoles in the cytoplasm
    4. karyorrhexis
      1. Ans(4)
  16. Apoptotic bodies are:
    1. clumped chromatin body
    2. pyknotic nucleus without organelles
    3. cell membrane bound with organelles
    4. no nucleus with organelles
      1. Ans(3)
  17. both hypertrophy and hyperplasia are seen in:
    1. pregnant uterus
    2. liver regeneration
    3. pancreas
    4. none
      1. Ans(1)
  18. All are true regarding apoptosis except
    1. chromatin is lysed by endonucleases to from nucleosomes
    2. it initiates local inflammatory reactions
    3. mecrophages phagocytose remaining apoptotic bodies
    4. caspases are increased and mediate apoposis
      1. Ans(2)
  19. Metaplasia arises from reprogramming of:
    1. stem cells
    2. stellate cells
    3. squamous cells
    4. columnar cells
      1. Ans(1)
  20. which of the following is an antiapoptotic gene?
    1. C-myc
    2. P53
    3. BCl-2
    4. Bax
      1. Ans(3)
  21. Coagulation necrosis is due to:
    1. denaturation of protein
    2. enzymatic digestion
    3. infection
    4. none
      1. Ans(1)
  22. ladder pattern of DNA electrophoresis in apoptosis is caused by the action of the following enzyme:
    1. endonuclease
    2. transglutaminase
    3. DNASE
    4. caspase
      1. Ans(1)
  23. Coagulation necrosis is seen in?
    1. TB
    2. sarcoidosis
    3. cryptococcal infection
    4. gangrene
      1. Ans(4)
  24. Annexin V is a marker of:
    1. Apoptosis
    2. necrosis
    3. atherosclerosis
    4. inflammation
      1. Ans(1)
  25. Caseous necrosis in granuloma not found in?
    1. tuberculosis
    2. leprosy
    3. histoplasmosis
    4. CMV
    5. wegener’s granulomatosis
      1. Ans(2)

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