NEET PG Pathology MCQs 2 – Cell – 2

  1. Epigenetics deals with genetic modification that does not alter the sequence of DNA. All of the following can defect epigenetic modifications except?
    1. Chip on chip
    2. bisulfite method
    3. HPLC
    4. methylation-specific PCR
      1. Ans(3)
  2. Which of the following is both morphogenic and mitogenic?
    1. insulin growth factor
    2. bone morphogenic factor
    3. fibroblast growth factor
    4. epidermal growth factor
      1. Ans(2,1)
  3. Coding of DNA constitutes what proportion of total DNA?
    1. 0.02
    2. 0.25
    3. 0.4
    4. 0.1
      1. Ans(1)
  4. the function of Proteoglycans and Hyaluronan is?
    1. Lubrication and reduces resistance
    2. cell growth
    3. conner ECM components
    4. provides tensile strength
      1. Ans(1)
  5. GWAS stands for:
    1. genome-wide Association syndrome
    2. genome-wide association studies
    3. genetic wide array studies
    4. genetic wide amplification studies
    5. the genetic way of association studies
      1. Ans(2)
  6. mutation in COL$A5 chain leads is:
    1. Alpert’s syndrome
    2. good pasture’s syndrome
    3. hereditary non-polyposis colon cancer
    4. Xeroderma pigmentosum
      1. Ans(1)
  7. Genetic polymorphism include
    1. SNP
    2. Microsatellites
    3. mutations
    4. translocation
    5. minisatellites
      1. Ans(1,2,3)
  8. oncogene tyrosine kinase involves:
    1. PML-BRCA 1
    2. BCR-ABL
    3. HAAJ
    4. JUN
    5. NJKK
      1. Ans(2,4)
  9. the function of miRNA is/are:
    1. gene silencing
    2. gene activation
    3. transcription inhibition
    4. translation repression
    5. the breaking of messenger RNA
      1. Ans(1,2,3)
  10. The epidermal growth factor is /are formed
    1. platelet
    2. fibroblast
    3. mast cell
    4. endothelial cell
    5. keratinocyte
      1. Ans(5)
  11. the most abundant glycoprotein present in the basement membrane is:
    1. laminin
    2. fibronectin
    3. collagen type 4
    4. heparan sulfate
      1. Ans(1)
  12. which of the following statements is not correct regarding stem cell?
    1. developmental elasticity
    2. transdifferentiation
    3. can be harvested from the embryo
    4. knock out mice made possible because of it
      1. Ans(1)
  13. All are components of the basement membrane except
    1. nidogen
    2. Laminin
    3. entactin
    4. rhodopsin
      1. Ans(4)
  14. which of the following is involved in stem cell self-renewal?
    1. Oct 3/4
    2. sox2
    3. c-myc
    4. FLT3
    5. c-kit
      1. Ans(1,2,4,5)
  15. Collagen most abundant in Hyaline cartilage
    1. type I
    2. type II
    3. type III
    4. type IV
      1. Ans(2)
  16. which of the following statements about hematopoietic stem cell is false?
    1. stem cells have self-renewal property
    2.  a subset of stem cells normally circulate in peripheral blood
    3. marrow-derived stem cells can seed other tissues and develop into non-hematopoietic cells as well
    4. stem cells resemble lymphoblasts morphologically
      1. Ans(2)
  17. most abundant collagen in the body?
    1. type I
    2. type II
    3. type III
    4. type IV
      1. Ans(2)
  18. In an ablated animal If Myeloid Stem cells are injected which type of cells are induced after the incubation period?
    1. T-lymphocyte
    2. erythroid
    3. fibroblast
    4. hematopoietic stem cells
      1. Ans(2)
  19. FACIT collagen is?
    1. type I
    2. type II
    3. type IX
    4. type XI
      1. Ans(3)
  20. True about stem cells
    1. found in the yolk sac
    2. used in gene therapy
    3. terminally matured cells
    4. found in peripheral circulation
    5. HLA DR positive
      1. Ans(1,2,5)
  21. Do gap junctions comprise of?
    1. catenins
    2. cadherins
    3. connexins
    4. claudin
      1. Ans(3)
  22. Location of small intestinal stem cells is?
    1. jejunum epithelial cells
    2. terminal ileum mucosa
    3. crypt base
    4. mucosa throughout
      1. Ans(3)
  23. All of the following are true about TGF-β except;
    1. anti-inflammatory
    2. causes fibrosis
    3. tumor suppressor gene
    4. anti-angiogenic
      1. Ans(4)
  24. true about stem cell
    1. undifferentiated
    2. pluripotent
    3. dedicated to one cell line
    4. used for cell repair and tissue regeneration
    5. can form any cell
      1. Ans(1,2,3,4)
  25. Which of the following statement is not true?
    1. cytokeratin is the marker of muscle cells
    2. vimentin is used to stain fibroblasts
    3. neurofilaments present in neurons
    4. desmin can be used as a marker for muscle cells
      1. Ans(1)

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