NEET PG Pathology MCQs 9 – Cell – 9

  1. Cell injury occurs due to:
    1. decreased ATP
    2. increased Ca 2+
    3. membrane damage
    4. mitochondrial dysfunction
    5. increased intracellular K+
      1. Ans(1,2,3,4)
  2. false about apoptosis?
    1. inflammation presents
    2. program cell death
    3. normal physiology
    4. genetically determined by a cell
      1. Ans(1)
  3. All of the following statements are true regarding reversible cell injury except:
    1. Formation of amorphous of adenosine in the mitochondrial matrix
    2. diminished generation of adenosine triphosphate
    3. formation of bleds in the plasma membrane
    4. a detachment of ribosomes from the granular endoplasmic reticulum
      1. Ans(1)
  4. Earliest changes in cell death are?
    1. Karyolysis
    2. loss of plasma membrane
    3. cell swelling
    4. karyorrhexis
      1. Ans(3)
  5. All are the reversible injury of the cell except:
    1. Vacuole
    2. karyorrhexis
    3. fat accumulation
    4. cell wall swelling
      1. Ans(2)
  6. Which of the following induces apoptosis?
    1. oleic acid
    2. mystic acid
    3. glucocorticoid
    4. isoprenoid
      1. Ans(4)
  7. Enzyme level in tissue injury is due to;
    1. lysis of cells
    2. enzyme secretion
    3. no inhibitor in serum
    4. all of the above
      1. As(1)
  8. Which of the following is an execution caspase
    1. Caspase 3
    2. caspase 5
    3. caspase 8
    4. caspase 9
      1. Ans(1)
  9. Cloudy swelling is due to;
    1. accumulation of water intracellularly
    2. fat accumulation intracellularly
    3. lysozyme degeneration
    4. glycogen accumulation intracellularly
      1. Ans(1)
  10. Diabetic foot is an example of:
    1. Dry gangrene
    2. wet gangrene
    3. gas gangrene
    4. necrotizing inflammation
      1. Ans(1)
  11. True about p53 gene?
    1. tumor suppression
    2. proapoptotic
    3. antiapoptotic
    4. cell repair
      1. Ans(1,2)
  12. Annexin V is a marker of:
    1. necrosis
    2. gangrene
    3. aging
    4. apoptosis
      1. Ans(4)
  13. true about caspases are?
    1. they are enzymes starting apoptosis
    2. they inhibit apoptosis
    3. they are receptors of apoptosis
    4. they are proteases which cause cellular death in apoptosis found in irreversible cell damage
      1. Ans(1,4)
  14. cell organelle which plays a pivotal role in apoptosis
    1. nucleus
    2. mitochondria
    3. golgi apparatus
    4. plasma membrane
      1. Ans(2)
  15. About given image true is?
    1. C is showing necrosis
    2. C is showing apoptosis
    3. C is showing normal cells
    4. A is showing apoptosis
      1. Ans(1)
  16. fibrinoid necrosis is seen in all except:
    1. malignant hypertension
    2. polyarteritis nodosa
    3. diabetic glomerulosclerosis
    4. rheumatic heart disease
      1. Ans(3)
  17. True about necroptosis is all except:
    1. caspase 1 & 11 in involved
    2. caspase-independent
    3. failure of activation of caspase 8
    4. lipid peroxidation is seen
      1. Ans(2,3)
  18. ladder pattern of DNA electrophoresis is seen in
    1. Necrosis
    2. apoptosis
    3. cytolysis
    4. karyorrhexis
      1. Ans(2)
  19. Which of the following is an antiapoptotic gene
    1. BAX
    2. BAD
    3. BCL-XL
    4. BIM
      1. Ans(3)
  20. The following is not a sensor of apoptosis
    1. puma
    2. Noxa
    3. Bax
    4. BAD
      1. Ans(3)
  21. SMAC/DIAMBLO is a
    1. Anti-apoptotic protein
    2. induces necrosis
    3. acts both as anti-pro-apoptotic protein
    4. Proapoptotic protein
      1. Ans(4)
  22. Intrinsic pathway of apoptosis is initiated by all the following except:
    1. growth factor withdrawal
    2. DNA damage
    3. protein misfolding
    4. type 1TNF receptor
      1. Ans(4)
  23. Antiapoptotic gene?
    1. FLIP
    2. P53
    3. BAX
    4. BIM
      1. Ans(1)
  24. Defective apoptosis and increased cell survival is seen in:
    1. autoimmune disease
    2. neurodegenerative disease
    3. viral infections
    4. ischemic injury
      1. Ans(1)
  25. Necrosis seen in chronic pancreatitis is?
    1. Fatty
    2. coagulative
    3. liquefactive
    4. casseous
      1. Ans(1)

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