NEET PG Pathology MCQs 22 – Inflammation and Repair – 12

  1. Wound contraction is mediated by:
    1. Myofibroblasts
    2. Epithelial cells
    3. Collagen
    4. Elastin
      1. Ans(1)
  2. Articular cartilage is made up of:
    1. Type I collagen
    2. Type II collagen
    3. Type III collagen
    4. Type IV collagen
      1. Ans(2)
  3. A fibroblast is derived from:
    1. Local mesenchyme
    2. Macrophage
    3. Endothelium
    4. Vessels
      1. Ans(1)
  4. Collagen most abundant in Hyaline cartilage
    1. Type 1
    2. Type II
    3. Type III
    4. Type IV
      1. Ans(2)
  5. Wound healing is the summation of the following processes except:
    1. Coagulation
    2. Matrix synthesis
    3. Angiogenesis
    4. fibro lysis
      1. Ans(1)
  6. The most abundant glycoprotein present in the basement membrane is:
    1. Laminin
    2. Fibronectin
    3. Collagen type 4
    4. Heparan sulfate
      1. Ans(1)
  7. Complete restoration of a tensile strength of the wound comparable to normal tissue take as long as
    1. Two weeks
    2. Six weeks
    3. Six months
    4. Two years
      1. Ans(3)
  8. Do integrins include all the following receptor except?
    1. Fibronectin
    2. Glycoprotein on the platelet surface
    3. Leukocyte adhesion molecule
    4. Platelet-derived growth factor
      1. Ans(4)
  9. All are labile except:
    1. Kupffer cell
    2. intestinal cells
    3. keratinocytes
    4. hepatocytes
      1. Ans(4)
  10. In Wound injury sequences of an appearance of cells is?
    1. Macrophage – Platelet – Neutrophils – fibroblasts
    2. Neutrophils – Macrophage—Platelet- fibroblast
    3. Platelet- Neutrophils – Macrophage -fibroblast
    4. Platelet- Macrophage- Neutrophils- fibroblast
      1. Ans(3)
  11. Maximum collagen in wound healing is seen at
    1. End of the first week
    2. End of the second week
    3. End of the third week
    4. End of 2 months
      1. Ans(2)
  12. Which is not seen in the inflammatory stage of wound healing?
    1. Angiogenesis
    2. Chemotaxis
    3. Increased capillary permeability
    4. Cytokine and chemotactic factor release
      1. Ans(1)
  13. During angiogenesis recruitment of pericytes and peri-endothelial cells is due to:
    1. VEGF & PDGF
    2. Angiopoietins, TGF & PDGF
    3. TGF,VEGF & PDGF
    4. VEGF, IL -2, IL-6
      1. Ans(2)
  14. Which of the following substance is a growth factor that is capable o including all the steps necessary for angiogenesis?
    1. Epidermal growth factor
    2. Transforming growth factor
    3. Platelet-derived growth factor
    4. Basic fibroblast growth factor
      1. Ans(4)
  15. Acid phosphatase is specific to which of the following cells:
    1. Monocyte
    2. T lymphocyte
    3. B lymphocyte
    4. Myelocytes
      1. Ans(1)
  16. Basement membrane degeneration is mediated by:
    1. Metalloproteinases
    2. Oxidases
    3. Elastases
    4. Hydroxylases
      1. Ans(1)
  17. All are components of basement membrane except:
    1. Nodogen
    2. Laminin
    3. Entactin
    4. Rhodopsin
      1. Ans(4)
  18. Wound healing is affected by
    1. age
    2. nutrition
    3. dryness or wetness of wound
    4. drugs
    5. temperature
      1. Ans(1,2,4,5)
  19. primary closure of incised wounds must be done within:
    1. 2 hours
    2. 4 hours
    3. 6 hours
    4. 12 hours
    5. 16 hours
      1. Ans(3)
  20. the tensile strength of wound reaches that of normal tissue by
    1. 6 weeks
    2. 2 months
    3. 4 months
    4. 6 months
    5. None
      1. Ans(5)
  21. Following are required for wound healing except:
    1. zinc
    2. copper
    3. vitamin C
    4. calcium
    5. None
      1. Ans(5)
  22. the vitamin which has an inhibitory effect on wound healing in:
    1. vitamin C
    2. vitamin E
    3. vitamin C
    4. Vitamin B -complex
      1. Ans(2)
  23. A Clean incised wound heals by:
    1. primary intention
    2. secondary intention
    3. excessive scarring
    4. none of the above
      1. Ans(1)
  24. Basement membrane degeneration is mediated by:
    1. Metalloproteinases
    2. Oxidases
    3. Elastases
    4. Hydroxylases
      1. Ans(1)
  25. All are components of the basement membrane except:
    1. Nodogen
    2. Laminin
    3. Entactin
    4. Rhodopsin
      1. Ans(4)

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