NEET PG Medicine MCQs 69 – Gastrointestinal and Biliary System Disorders

1. Which one of the following serum levels would help in distinguishing an acute liver disease from chronic liver disease?

  1. Aminotransaminase
  2. Alkaline phosphatase
  3. Bilirubin
  4. Albumin


2. Quantitative assessment of liver function can be done by:

  1. Degree of Transaminases
  2. The degree of Alkaline phosphatase
  3. Degree of GGT
  4. Estimation of Galactose Elimination capacity


3. The Maddrey discriminant score is used for determining mortality due to

  1. Alcoholic hepatitis
  2. Viral hepatitis
  3. Cryptogenic hepatitis
  4. Hepatic encephalopathy

Ans (1)

4. Milan criteria are used for

  1. Liver transplantation
  2. GERD staffing
  3. Cirrhosis staging
  4. Hepatic encephalopathy staging

Ans (1)

5. Increased LDH is an important marker for

  1. Bulky disease
  2. Lymphoma
  3. Liver metastasis
  4. Lung metastasis

Ans (1)

6. Menghini’s needle is used for

  1. Pleural aspiration
  2. Lumbar puncture
  3. Kidney biopsy
  4. Liver biopsy

Ans (4)

7. What is the uppermost intercostals space used for hepatic biopsy

  1. 5th
  2. 7th
  3. 9th
  4. 11th

Ans (2)

8. Investigation of choice to confirm Hemochromatosis as the cause of cardiomyopathy is

  1. ECG
  2. Echo
  3. MRI
  4. CT

Ans (3)

9. The first test to become positive in patients with hemochromatosis is

  1. Increased serum iron
  2. Increased serum ferritin
  3. Increased transferrin saturation
  4. Increased liver enzymes

Ans (3)

10. A patient presents with fasting blood sugar of 167mg/dl, skin pigmentation, and hypogonadism. His liver enzymes show SGOT as 670 and SGPT as 690. Which of the following is the most likely diagnosis?

  1. Alpha-I antitrypsin Deficiency
  2. Wilson’s disease
  3. Hemochromatosis
  4. Glycogen storage disease

Ans (3)

11. A patient presents with Arthritis, hyperpigmentation of skin and hypogonadism, likely diagnosis is

  1. Hemochromatosis
  2. Ectopic ACTH secreting tumor of the lung
  3. Wilson’s disease
  4. Rheumatoid arthritis

Ans (1)

12. A 14-year-old boy presents with recurrent episodes of hepatitis ophthalmoscopic evaluation reveals KF rings and serum ceruloplasmin levels are < 20 mg/dl. The treatment of choice for initial therapy is

  1. Zinc
  2. Penicillamine
  3. Tetrathiomolybdate
  4. Hepatic transplantation

Ans (1)

13. Kayser – Fleischer rings (KF rings) are seen in

  1. Pterygium
  2. Hematochromatosis
  3. Wilson’s disease
  4. Menke’s kinked hair syndrome

Ans (3)

14. A 12 years old girl with tremors and emotional liability has golden brown discoloration in liability has golden brown discoloration in liability has golden brown discoloration in Descemet’s membrane. The most likely diagnosis is

  1. Fabry’s disease
  2. Wilson’s disease
  3. Glycogen storage disease
  4. Acute Rheumatic fever

Ans (2)

15. All of the following statements about Wilson’s disease are true, except

  1. Autosomal dominant inheritance
  2. Hemolytic anemia
  3. Low serum ceruloplasmin
  4. Mutation on chromosome 13

Ans (1)

16. All the following are features of Wilson’s disease except

  1. Increased copper content in liver
  2. Increased ceruloplasmin
  3. Mental changes
  4. Features of chronic active hepatitis

Ans (2)

17. Which of the following does not predispose to Cholangiocarcinoma

  1. Ulcerative colitis
  2. Clonorchis sinensis
  3. Choledochal cyst
  4. Chronic pancreatitis

Ans (2))

18. Tokyo guidelines are used for diagnosis and severity assessment of

  1. Acute Appendicitis
  2. Acute Cholecystitis
  3. Acute Pancreatitis
  4. Irritable Bowel Syndrome

Ans (2)

19. Charcot’s triad includes all of the following except

  1. Pain
  2. Fever
  3. Jaundice
  4. Vomiting

Ans (4)

20. All of the following are required for visualization of gall bladder in an oral cholecystogram except

  1. Motor mechanism of gall bladder
  2. Patency of cystic duct
  3. Ability to absorb water
  4. Functioning hepatocytes

Ans (1)

21. A 69-year-old male patient having coronary artery disease was found to have gall bladder stones while undergoing a routine ultrasound of the abdomen. There was no history of biliary colic or jaundice at any time. What is the best treatment advice for such a patient for his gallbladder stones:

  1. Open Cholecystectomy
  2. Laparoscopic cholecystectomy
  3. No surgery for gallbladder stones
  4. ERCP and removal of gallbladder stones

Ans (3)

22. The treatment of choice for silent stones in Gall bladder is

  1. Observation
  2. Chenodeoxycholic acid
  3. Cholecystectomy
  4. Lithotripsy

Ans (1)

23. In males the amount of ethanol consumed per day that can cause fatty liver is

  1. 10-20g/day
  2. 20-40g/day
  3. 40-80g/day
  4. 60-80g/day

Ans (3)

24. The genetic factor in alcoholic liver disease

  1. phatatin like phospholipase domain-containing protein 3(PNPLA3)
  2. PTEN induced putative kinase 1 (PINK 1)
  3. myelocytomatosis viral oncogene (MVC)
  4. toll-like receptor 4

Ans (1)

25. All are true about alcoholic liver disease except

  1. in a stage of steatosis liver function test is normal
  2. stage of hepatitis is due to direct oxidative injury
  3. transforming growth factor beta (TGF-β)facilitates apoptosis and necrosis in the stage of hepatitis
  4. stellate cell-mediated fibrosis leads to cirrhosis

Ans (3)

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Most of the questions are from previous papers of  leading universities in India

Repeat questions show the importance of those questions


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