NEET PG Medicine MCQs 87 – Renal System Disorders

1. The prognosis of rapidly proliferating glomerulonephritis (Crescentric GN) depends upon-

  1. Number of crescents
  2. Size of crescents
  3. Shape of crescents
  4. Cellularity of crescents

Ans(1)


2. A 30-year-old man presents with generalized edema and hypertension. Urine examination shows subnephrotic proteinuria (<2gm) and microscopic hematuria. Serum complement levels are decreased and he is positive for anti-hepatitis C antibodies. The most likely diagnosis is:

  1. Post-streptococcal Glomerulonephritis (PSGN)
  2. Cryoglobulinemia
  3. Membranoproliferative Glomerulonephritis (MPGN)
  4. Focal Segmental Glomerular Sclerosis (FSGS)

Ans(2,3)


3. Which of the following is not true about Berger’s disease?

  1. The pathological changes are proliferative and usually confined to mesangial cells, usually focal and segmental
  2. Hematuria may be gross or microscopic
  3. On immunofluorescence, deposits contain both IgA and IgG
  4. The absence of associated proteinuria is pathognomonic

Ans(4)


4. Increased IgA deposits are seen in:

  1. Henoch Schonlein Purpura
  2. Minimal change Glomerulonephritis
  3. Chronic Pyelonephritis
  4. Haemolytic Uremic Syndrome

Ans(1)


5. The most common presentation of IgA nephropathy is:

  1. Nephritic syndrome
  2. Nephritic syndrome
  3. Microscopic hematuria
  4. Repeated gross hematuria

Ans(4)


6. Marker for the renal vasculitis in children is –

  1. Increased IgA level
  2. Low complement level
  3. Antineutrophilic cytoplasmic antibody titer

Ans(1)


7. A six-year-old male baby presents in a hospital with recurrent gross hematuria for 2 years. There is no h/o burning micturition or pyuria. Urine routine examination demonstrated no pus cells and urine culture was sterile. Serum C3 levels were normal. What is the most probable diagnosis:

  1. Wilm’s tumor
  2. IgA nephropathy
  3. Post-streptococcal glomerulonephritis
  4. Urinary tract infection

Ans(2)


8. A female patient Nandini presents with upper respiratory tract infection. After 15 days, she develops hematuria Probable diagnosis is:

  1. IgA nephropathy
  2. Wegener’s granulomatosis
  3. Henoch Schlein purpura
  4. Post-streptococcal glomerulonephritis

Ans(4)


9. A patient presents with hemoptysis and hematuria a few weeks after a respiratory tract infection. ANCA antibodies are present. Likely diagnosis is:

  1. Goodpasture’s syndrome
  2. IgA Nephropathy
  3. Nephrotic syndrome
  4. PSGN

Ans(1)


10. A 25-year-old boy presents with renal failure. His uncle died of renal failure three years ago. Slit lamp examination reveals Lenticonus / Keratoconus. The likely diagnosis is:

  1. Autosomal Dominant Polycystic Kidney (ADPCKD)
  2. Autosomal recessive polycystic kidney (ARPCKD)
  3. Alport’s syndrome
  4. Denish-Drash Syndrome

Ans(3)


11. Typical features of Lipoid nephrosis include:

  1. Normal light microscopy
  2. FSGS
  3. Glomerular tuft sclerosis
  4. Effacement of foot processes
  5. Tubular sclerosis

Ans(4)


12. Clinical features of minimal change: glomerulonephritis is all except:

  1. Hypertension
  2. Edema
  3. Selective proteinuria
  4. Fever

Ans(1)


13. Minimal change glomerulopathy may be seen in association with all of the following except:

  1. Hepatitis B
  2. HIV
  3. Drug-induced interstitial nephritis
  4. Hodgkin’s disease

Ans(1)


14. All are steroid resistant except:

  1. Post-streptococcal glomerulonephritis
  2. Minimal change glomerulonephritis
  3. RPGN
  4. Recurrent hematuria

Ans(2)


15. Most common pathological features in diabetes mellitus are:

  1. Papillary necrosis
  2. Diffuse glomerulosclerosis
  3. Renal atherosclerosis
  4. Chronic pyelonephritis

Ans(2)


16. Which of the following is the first clinically detectable sign of diabetic nephropathy:

  1. Serum creatinine
  2. Creatinine clearance
  3. Microalbuminuria
  4. Macroalbuminuria

Ans(3)


17. The earliest clinical feature of diabetic nephropathy is:

  1. Microalbuminuria
  2. Increased serum creatinine
  3. Nephritic syndrome
  4. Hematuria

Ans(1)


18. The preferred method for determining microalbuminuria is:

  1. Urinary dipsticks
  2. 24-hour urinary protein collection
  3. Urinary A/C Ratio in a spot voided sample
  4. Urinary A/C ratio in a 24-hour collection

Ans(3)


19. Pathological changes of diabetic nephropathy are all except:

  1. Fibrin caps and capsular drops
  2. Intercapillary glomerulosclerosis
  3. Focal sclerosis
  4. Capillary basement membrane thickening

Ans(3)


20. The Recommended treatment of early diabetic nephropathy manifested by microalbuminuria is :

  1. Strict glycemic control
  2. Low Protein Diet
  3. Strict glycemic control and Low Protein Diet
  4. Strict glycemic control, Low protein diet and ACE Inhibitors

Ans(3)


21. The term ‘HIVAN’ is used for:

  1. FSGS
  2. Acute diffuse proliferative glomerulonephritis
  3. IgA nephropathy
  4. Membranous glomerulopathy

Ans(1)


22. Minimal change disease patients with steroid resistance can develop:

  1. FSGS
  2. Mesangioproliferative glomerulonephritis
  3. Microscopic polyangiitis
  4. Membranous Glomerulonephritis

Ans(1)


23. Logbar glomerulonephritis is also called as :

  1. FSGS
  2. Membranous glomerulonephritis
  3. MPGN
  4. Minimal Change Disease

Ans(3)


24. Dense deposit disease includes:

  1. MPGN type I
  2. MPGN type II
  3. MPGN type III
  4. All of the above

Ans(2)


25. Which cause of nephrotic syndrome have highest incidence of thrombotic complications:

  1. Minimal Change Disease
  2. FSGS
  3. Membranous Glomerulonephritis
  4. Diabetic Nephropathy

Ans(3)


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