NEET PG Medicine MCQs 118 – Connective Tissue Disorders- 1

  1. All of the following are true about Drug-induced Lupus; Except:
    1. Anti-histone antibody
    2. rare anti-ds DNA
    3. Renal involvement
    4. serositis
      1. Ans(3)
  2. Bilateral parotid enlargement occurs in all Except
    1. Sjogren’s syndrome
    2. SLE
    3. HIV
    4. chronic pancreatitis
      1. Ans(2)
  3. Antibodies most commonly seen in drug-induced lupus are:
    1. Anti-ds DNA antibodies
    2. Anti – Sm Antibodies
    3. Anti-Ro Antibodies
    4. Antihistone Antibodies
      1. Ans(4)
  4. Bilateral parotid enlargement is seen in all of the following except:
    1. sarcoidosis
    2. SLE
    3. Chronic pancreatitis
    4. Sjogren’s syndrome
      1. Ans(2)
  5. In SLE characteristic kidney lesion is:
    1. Mesangial proliferation
    2. Tubular fibrin deposits
    3. Wire loop lesions
    4. IgG deposits
      1. Ans(3)
  6. The indication of steroids in SLE are all except:
    1. Myocarditis
    2. Neuropsychiatric syndrome
    3. Thrombocytopenia
    4. Endocarditis
      1. Ans(4)
  7. Wire loop-lesions are often characteristic for the following class of lupus nephritis:
    1. mesangial proliferative glomerulonephritis
    2. focal proliferative glomerulonephritis
    3. diffuse proliferative  glomerulonephritis
    4. membranous glomerulonephritis
      1. Ans(3)
  8. Low doses of aspirin therapy are essentially advised for all of the following conditions except:
    1. SLE
    2. IUGR
    3. post myocardial infarction
    4. preeclampsia
      1. Ans(1)
  9. 30 years old Basanti presents with light brown lesions involving both her checks. The lesions had never been erythematous. Which of the following is the most probable diagnosis:
    1. SLE
    2. Chloasma
    3. Airborne contact dermatitis
    4.  photosensitive reaction
      1. Ans(1)
  10. All of the following are true about Rheumatoid arthritis except:
    1. Positive for Anti-IgG antibody
    2. Juxta-articular osteoporosis
    3. Morning stiffness
    4. C – reactive protein indicates a better prognosis
      1. Ans(4)
  11. A female developed brown macule on the check forehead and nose after exposure to light following delivery of a baby, the diagnosis is:
    1. SLE
    2. Chloasma
    3. photodermatitis
    4. Acne rosacea
      1. Ans(2)
  12. Which of the following is true regarding Rheumatoid arthritis:
    1. Typically involves small and large joints symmetrically but spares the cervical spine
    2. causes pleural effusion with low sugar
    3. pulmonary nodules are ancient
    4. enteropathy prominent
      1. Ans(2)
  13. Antiphospholipid antibody syndrome is associated with all of the following except:
    1. bleeding disorders
    2. Thrombotic disorders
    3. coagulation disorders
    4. recurrent fetal loss
      1. Ans(1)
  14. All of the following are true about Rheumatoid Arthritis, except:
    1. PIP and DIP joints involved equally
    2. pathology limited to articular cartilage women are affected 3 times more commonly than men
    3. Rheumatoid nodules are seen in 20%of patents
    4. 20 percent of patients have extra-articular manifestations
      1. Ans(1,2)
  15. All of the following statements about Antiphospholipid Antibody Syndrome are true except:
    1. The single titer of Anticardiolipin is diagnostic
    2. Commonly presents with recurrent fetal loss
    3. may cases pulmonary hypertension
    4. Warfarin is given as treatment
      1. Ans(1)
  16. Which of the following is not a characteristic deformity associated with rheumatoid arthritis?
    1. Swan -neck deformity
    2. heberden node
    3. Boutonniere deformity
    4. ulnar deviation
      1. Ans(2)
  17. Anti Phospholipid Syndrome is associated with all of the following except:
    1. Pancytopenia
    2. Recurrent abortions
    3. Venous thrombosis
    4. pulmonary hypertension
      1. Ans(1)
  18. Middle-Aged female presents with polyarthritis elevated Rheumatoid factor and ANA levels. Which Rheumatoid arthritis from SLE
    1. Soft tissue swelling in PIP joint
    2. Juxta-articular osteoporosis on X -ray
    3. Articular erosions on X-Ray
    4. Elevated ESR
      1. Ans(3)
  19. Lupus Anticoagulants may cause all of the following except:
    1. Recurrent abortion
    2. false +ve VDRL results
    3. Increase prothrombin time
    4. Arterial thrombosis
      1. Ans(3)
  20. True regarding felty’s syndrome is all except:
    1. splenomegaly
    2. Rheumatoid arthritis
    3. neutropenia
    4. Nephropathy
      1. Ans(4)
  21. The following conditions are not associated with an Anti-phospholipid syndrome:
    1. venous thrombosis
    2. recurrent foetal loss
    3. thrombocytosis
    4. neurological manifestations
      1. Ans(3)
  22. Which part of the spine is most commonly affected in Rheumatoid arthritis:
    1. Cervical
    2. Lumbar
    3. Thoracic
    4. sacral
      1. Ans(1)
  23. Features of SLE includes all  of the following except:
    1. recurrent abortion
    2. sterility
    3. coomb’s positive hemolytic anemia
    4. psychosis
      1. Ans(2)
  24. Which radiological features would help differentiate rheumatoid arthritis with SEL?
    1. Erosion
    2. Juxta-articular osteoporosis
    3. subluxation of MCP joint
    4. swelling of PIP joint
      1. Ans(1)
  25. Which of the following is recommended in a woman with Antiphospholipid Antibodies and history of prior abortions/ stillbirth:
    1. Aspirin only
    2.  Aspirin +low molecular weight +Heparin
    3.  Aspirin +low molecular weight +Heparin +Prednisolone
    4. No treatment
      1. Ans(2)

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