NEET PG Medicine MCQs 121 – Connective Tissue Disorders – 4

  1. Treatment of choice in seronegative spondylarthritis is:
    1. Phenylbutazone
    2. Aspirin
    3. Indomethacin
    4. Corticosteroid
      1. Ans(3)
  2. Risk factors associated with the development of Gout include all of the following Except:
    1. Female sex
    2. alcohol
    3. Hyperlipidemia
    4. Hypertension
      1. Ans(1)
  3. A 35 years old male develops involvements of PIP DIP and metacarpophalangeal joints with sparing of the wrist and carpometacarpal joints. The probable diagnosis is:
    1. Psoriatic arthropathy
    2. Osteoarthritis
    3. Rheumatoid Arthritis
    4. Pseudo Gout
      1. Ans(1)
  4. Gout can be precipitated by all of the following except:
    1. Thiazides
    2. Furosemide
    3. Cyclosporine
    4. high Dose Salicylates
      1. Ans(4)
  5. A patient presents with foreign body sensation in the eye and swollen knee joint after a leisure trip. The most probable diagnosis is:
    1. sarcoidosis
    2. Reiter’s disease
    3. Behcet’s disease
    4. SLE
      1. Ans(2)
  6. All of the following statements about primary Gouty Arthritis are true  Except:
    1. 90% of cases are caused by overproduction of uric acid
    2. Uric acid levels may be normal at the time of an acute attack
    3. men are more commonly affected than women (male>female)
    4. defective diagnosis requires aspiration of synovial fluid
      1. Ans(1)
  7. Urethritis is seen in:
    1. Reiter’s syndrome
    2. Gout
    3. Rheumatoid Arthritis
    4. PAN
      1. Ans(1)
  8. All of the following are true about Gout, except:
    1. occurs due to an accumulation of urate crystals in joint
    2. can be pptd by pyrazinamide
    3. Birefringent crystals are presents in joint
    4. Occurs more in female
    5. due to decreased excretion of uric acid
      1. Ans(4)
  9. What is not seen in Reiters syndrome
    1. Subcutaneous blennorrhagicum
    2. Keratoderma blennorrhagicum
    3. Circinate balanitis
    4. Oral ulcers
      1. Ans(1)
  10. Which of the following is associated with high Risk of developing a potentially life-threatening reaction to allopurinol
    1. HLA -B 51 gene marker
    2. HLA -B 5801 gene marker
    3. HLA -B 27 gene marker
    4. Non of the above
      1. Ans(2)
  11. Which of the organism most commonly causes reactive arthritis?
    1. Ureaplasma Urealyticum
    2. Group A beta-hemolytic streptococci
    3. Borrelia Burgdorfer
    4. Chlamydia
      1. Ans(4)
  12. Keratoderma Blenorrhagica is typically seen in:
    1. Rheumatoid Arthritis
    2. psoriatic arthritis
    3. reactive arthritis
    4. ankylosing spondylitis
      1. Ans(3)
  13. Which of the following statements is TRUE regarding arthritis associated with Inflammatory bowel disease?
    1. sacroiliitis may be presented in some cases
    2. It always predates the onset of bowel disease
    3. It predominantly affects small joints of hands
    4. The treatment of bowel disease worsens the arthritis
      1. Ans(1)
  14. All of the following Drugs are used in the treatment of chronic gout, except:
    1. allopurinol
    2. benzbromarone
    3. Pegloticase
    4. Methotrexate
      1. Ans(4)
  15. Proximal interphalangeal distal interphalangeal & Ist carpometacarpal joint involvement and sparing of the wrist is a feature of:
    1. Rheumatoid Arthritis
    2. Pseudogout
    3. psoriatic arthropathy
    4. osteoarthritis
      1. Ans(4)
  16. Which of the following is NOT true regarding the treatment of acute gout?
    1. NSAIDS
    2. Colchicine
    3. Allopurinol
    4. Glucocorticoid
      1. Ans(3)
  17. Least common site to be involved in osteoarthritis amongst the following  is:
    1. Hip joint
    2. Knee joint
    3. carpometacarpal joint of the thumb
    4. metacarpophalangeal joint
      1. Ans(4)
  18. Uricase used in the treatment of chronic gout is:
    1. Allopurinol
    2. Benzbromarone
    3. Pegloticase
    4. Methotrexate
      1. Ans(3)
  19. A 35 years old male patient develops involvement of proximal and distal interphalangeal joint and 1st canpo-metacarpal joint with sparing of the wrist and metacarpophalangeal joint. The diagnosis is:
    1. Osteoarthritis
    2. psoriatic arthropathy
    3. Rheumatoid Arthritis
    4. Pseudogout
      1. Ans(1)
  20. All of the following statement about is an attack of gouty arthritis are true except:
    1. Joint aspirate reveals negative birefringent crystals
    2. Allopurinol should be started immediately
    3. colchicine is known to provide relief
    4. serum uric acid levels may be normal
      1. Ans(2)
  21. Herbeden’s arthropathy affects
    1. Lumbar spine
    2. symmetrically large joints
    3. sacroiliac joints
    4. distal interphalangeal joints
      1. Ans(4)
  22. All of the following conditions are observed in Gout except:
    1. Uric acid nephrolithiasis
    2. Deficiency of enzyme Xanthine oxidase
    3. Increase in serum urate concentration
    4. Renal Disease involving interstitial tissue
      1. Ans(2)
  23. A 35 years old male develops involvements of PIP DIP and metacarpophalangeal joints with sparing of the wrist and carpometacarpal joints. The probable diagnosis is:
    1. Psoriatic arthropathy
    2. Osteoarthritis
    3. Rheumatoid Arthritis
    4. Pseudo Gout
      1. Ans(1)
  24. Gout is a disorder os:
    1. Purine Metabolism
    2. pyrimidine metabolism
    3. ketone metabolism
    4. protein metabolism
      1. Ans(1)
  25. Clinical features of Gout include:
    1. severe joint pain
    2. involvement of small joints
    3. Deposition of monosodium urate crystals in synovium
    4. Chondrocalcinosis
    5. all of the above
      1. Ans(5)

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