NEET PG Medicine MCQs 126 – Connective Tissue Disorders- 9

 

1. Henoch – Schonlein purpura is characterized by the deposition of the following immunoglobulin around the vessels:

  1. IgM
  2. IgG
  3. IgA
  4. IgE

Ans(3)


2. Henoch-Schonlein-Purpura is characterized by the deposition of which of the following immunoglobulin around the vessels?

  1. IgA
  2. IgE
  3. IgG
  4. IgM

Ans(1)


3. Henoch Schonlein Purpura presents with deposition of:

  1. IgG
  2. IgM
  3. IgA
  4. IgE

Ans(3)


4. All of the following are features of Behcet’s syndrome except:

  1. Recurrent aphthous stomatitis
  2. Multi-system involvement
  3. Seen only in the tropics
  4. Common in youngster

Ans(3)


5. Behcet’s syndromes are characterized by all except:

  1. Myocarditis
  2. Erythema Nodosum
  3. Oral and Genital ulcers
  4. Thrombophlebitis

Ans(1)


6. Recurrent Bilateral Hypopyon formation associated with thrombophlebitis is most consistent with which of the following:

  1. HLA B 27 associated uveitis
  2. Behcet’s syndrome
  3. Syphilis
  4. Herpes Zoster

Ans(2)


7. Type I Cryoglobulinemia is associated with all of the following except:

  1. Hyperviscosity
  2. Monoclonal IgM paraprotein
  3. Normal complement levels
  4. Strongly Positive rheumatoid factor

Ans(4)


8. All of the following statements about Kawasaki disease are true, Except:

  1. Immunoglobulin is the treatment of choice
  2. Prognosis is good
  3. Thrombocytopenia
  4. Elevated ESR

Ans(3)


9. Which of the following statements regarding Kawasaki disease is True:

  1. Associated with coronary artery aneurysm in up to 25% of untreated cases
  2. It is the most common cause of vasculitis in children
  3. IV immunoglobulins are recommended only if the coronary artery is involved
  4. Lymph node biopsy is used for diagnosis

Ans(1)


10. All are features of Kawasaki disease except:

  1. Peak incidence at age > 5 years
  2. Aneurysm of coronary artery
  3. Enlarged lymph nodes
  4. Fever

Ans(1)


11. An elderly female presents to the emergency department with a history of fever, headache, and double vision. Biopsy of the temporal artery revealed panarteritis. The most likely diagnosis is:

  1. Nonspecific Arteritis
  2. Polyarteritis Nodosa
  3. Wegener’s Granulomatosis
  4. Temporal Arteritis

Ans(4)


12. Which of the following is the most frequent presenting symptoms in patients with giant cell arteritis:

  1. Headache
  2. Jaw claudication
  3. Polymyalgia Rheumatica
  4. Blindness

Ans(1)


13. Jaw tightness is typically seen in:

  1. PAN
  2. Coarctation of aorta
  3. Giant cell arteritis
  4. Wegner’s Granulomatosis

Ans(3)


14. All of the following statements about temporal arteritis are true, except:

  1. More common in females
  2. Worsens on exposure to heat
  3. Seen in elderly women
  4. Can lead to sudden bilateral blindness

Ans(2)


15. ANCA positive vasculitis includes all of the following except:

  1. Wegner’s granulomatosis
  2. Church Strauss syndrome
  3. Microscopic PAN
  4. Good pasture’s syndrome

Ans(4)


16. ANCA is NOT associated with which of the following disease:

  1. Wegener’s Granulomatosis
  2. Henoch Schonlein Purpura
  3. Microscopic Polyangiitis
  4. Churg Strauss syndrome

Ans(2)


17. ANCA is NIT associated with which of the following disease:

  1. Wegener’s granulomatosis
  2. Henoch schonlein purpura
  3. Microscopic PAN
  4. Churg Strauss syndrome

Ans(2)


18. ACNA is sensitive and specific for:

  1. Post-streptococcal glomerulonephritis
  2. Idiopathic crescentic glomerulonephritis
  3. Diffuse glomerulosclerosis
  4. Henoch’s schonlein purpura

Ans(2)


19. CANCA Positivity is specific for:

  1. Polyarteritis Nodosa
  2. Wegener’s granulomatosis
  3. Henoch contain purpura
  4. Churg Strauss syndrome

Ans(2)


20. An 18-year-old boy presents with digital gangrene in 3rd and 4th fingers for last 2 w33ks. On examination, the BP is 170/110 mm of Hg and all peripheral pulses were palpable. Blood & Urine examination were unremarkable. Antinuclear antibody, Antibody to ds DNA & DNA & ANCA were negative. Most likely diagnosis is:

  1. Henoch-Schonlein purpura
  2. Polyarteritis nodosa
  3. Wegener’s granulomatosis
  4. Disseminated tuberculosis

Ans(2)


21. A 30-year-old male presents with numbness of both lower limbs and right upper limb. Examination reveals pulse 88/minutes and BPI 160/110 mm of Hg. He also has digital gangrene involving right 2nd and 3rd finger, urine routine examination is unremarkable, microscopic examination shows RBC’s Hemogram and serum biochemistry is within normal limits. What is the most probable diagnosis?

  1. Systemic lupus erythematosus
  2. Polyarteritis nodosa
  3. Malignant hypertension
  4. Chugh-Strauss syndrome

Ans(2)


22. A patient presents with melaena normal renal function, hypertension, and mononeuritis multiplex. The most probable diagnosis is:

  1. Classical polyarteritis nodosa
  2. Microscopic polyangiitis
  3. Henoch-Schonlein purpura
  4. Buerger’s disease

Ans(1)


23. Biopsy in PAN shows:

  1. Necrotizing arteritis
  2. Atrophy
  3. Granulomatous lesion
  4. Ring lesion

Ans(1)


24. Which of the following is not true about Churg-Strauss Syndrome:

  1. Asthma
  2. Peripheral eosinophilia
  3. Vasculitis of multiple organ systems
  4. Intravascular Granulomas

Ans(4)


25. Which of the following is most commonly involved in Hypersensitivity vasculitis:

  1. Capillaries
  2. Arterioles
  3. Post-capillary venules
  4. Medium sized arteries

Ans(3)


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