Lesson 131 – NEET PG Medicine MCQs 131 – Hematology – 4

 

1. All of the following are causes of fragmented RBC in peripheral blood Except:

  1. I.C
  2. Hemophilia – A
  3. Malignant hypertension
  4. HELLP syndrome

Ans(2)


2. 1 25-year old pregnant lady presents with thrombocytopenia (Platelet count < 50,000) and fragmented RBC’s in peripheral smear. Which of the following is the least likely differential diagnosis?

  1. Thrombotic Thrombocytopenic Purpura (TTP)
  2. Disseminated Intravascular Coagulation (DIC)
  3. HELLP syndrome
  4. Evan’s syndrome

Ans(4)


3. The differential diagnosis of micro-angiopathic anemia includes all except:

  1. Sepsis
  2. Hemolytic uremic syndrome
  3. MI
  4. Eclampsia
  5. Scleroderma

Ans(3)


4. Microangiopathic Hemolytic anemia is seen in all except:

  1. TTP
  2. Metallic heart valve
  3. Microscopic polyangiitis
  4. Anti-phospholipid syndrome

Ans(2)


5. Microangiopathic hemolytic anemia is seen in all except:

  1. HUS
  2. ITP
  3. Malignant hypertension
  4. Prosthetic valves
  5. TTP

Ans(2)


6. Schistocytes are seen in:

  1. Aplastic anemia
  2. Megaloblastic anemia
  3. Iron deficiency anemia
  4. Microangiopathic hemolytic anemia

Ans(4)


7. All of the following can be associated with PNH except:

  1. Cerebral thrombosis
  2. Budd Chiari syndrome
  3. Pancytopenia
  4. Massive splenomegaly

Ans(4)


8. All are true regarding paroxysmal nocturnal hemoglobinuria except:

  1. Haemosiderinuria
  2. Pancytopenia
  3. Increased alkaline phosphatase
  4. Cellular marrow

Ans(3)


9. PNH is associated with all of the following conditions, except:

  1. Aplastic anemia
  2. ed LAP scores
  3. Venous thrombosis
  4. Iron deficiency anemia

Ans(2)


10. A stem cell disorder affecting all the three cell lines platelets, RBCs and leucocytes are:

  1. Hemolytic anemia
  2. Paroxysmal cold hemoglobinuria
  3. Paroxysmal nocturnal hemoglobinuria
  4. Blackfan Diamond syndrome

Ans(3)


11. All of the following are true about PNH, except:

  1. Hypocellular marrow
  2. Budd-Chiari syndrome
  3. Thrombosis
  4. LAP score low

Ans(1)


12. Which of the following is NOT seen in Paroxysmal Nocturnal Hemoglobinuria:

  1. Thrombosis
  2. Hemosiderinuria
  3. Decreased LDH
  4. Thrombocytopenia

Ans(3)


13. PNH is associated with a deficiency of:

  1. DAF
  2. MIRL
  3. GPI Anchored protein
  4. All of the above

Ans(4)


14. PNH is associated with deficiency of:

  1. DAF (Decay-accelerating factor)
  2. MIRL (Membrane inhibitor of reactive lysis)
  3. GPI Anchored Proteins (Glycosyl phosphatidyl Inositol anchored proteins)
  4. LFA (Lymphocyte function associated antigen)

Ans(3)


15. The gold standard test for the diagnosis of Paroxysmal Nocturnal Hemoglobinuria (PNH) is:

  1. Flow cytometry
  2. Sucrose hemolysis test
  3. HAM test
  4. Genetic testing

Ans(1)


16. HAM test is based upon:

  1. GPI Anchor Proteins
  2. Complement
  3. Spectrin protein
  4. Mannose-binding proteins

Ans(2)


17. All of the following are examples of diseases causing Aplastic anemia except:

  1. PNH
  2. Hepatitis
  3. Pregnancy
  4. Cold hemoglobinuria

Ans(4)


18. Aplastic anemia is seen in all of the following except1. PNH

  1. Chloramphenicol
  2. Hepatitis A
  3. HIV-1
  4. Parvovirus

Ans(4)


19. Pancytopenia with cellular marrow is seen in:

  1. PNH
  2. G6PD deficiency
  3. Acquired aplastic anemia
  4. Thalassemia

Ans(4)


20. Pancytopenia with hypercellular marrow may be seen due to all of the following except:

  1. Myelodysplasia
  2. Paroxysmal Nocturnal Hemoglobinuria
  3. Dyskeratosis congenital
  4. Sarcoidosis

Ans(1)


21. Which of the following causes of Anemia is associated with a Hypoplastic marrow:

  1. Fanconi’s Anemia
  2. Paroxysmal Nocturnal Hemoglobinuria (PNH)
  3. Hypersplenism
  4. Myelofibrosis

Ans(2)


22. Pancytopenia with hypercellular bone marrow is seen in:

  1. PNH
  2. Megaloblastic anemia
  3. Acquired aplastic anemia
  4. Thalassemia

Ans(1)


23. Pancytopenia with Cellular marrow is seen in all except:

  1. Megaloblastic Anemia
  2. Myelodysplasia
  3. PNH
  4. G6PD Deficiency

Ans(1)


24. Pancytopenia with a cellular marrow is seen in all except:

  1. PNH
  2. Megaloblastic anemia
  3. Myelodysplastic syndrome
  4. Dyskeratosis congenital

Ans(2)


25. All of the following are causes of pancytopenia with cellular bone marrow except:

  1. Paroxysmal nocturnal hemoglobinuria
  2. Dyskeratosis congenital
  3. Megaloblastic anemia
  4. Hairy cell leukemia

Ans(3)


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